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–+ servings
southwest chicken bake in casserole dish
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4.45 from 81 votes

Southwest Chicken Recipe

This southwest chicken bake is a cheesy enchilada-inspired dish the whole family will devour! This creamy baked chicken is so tasty and so easy to make.
Prep Time10 minutes
Cook Time20 minutes
Total Time30 minutes
Course: Main Course
Cuisine: Mexican
Servings: 4
Calories: 514kcal
Author: Becky Hardin

Equipment

  • 8x11-inch Baking Dish

Ingredients

  • 4 boneless, skinless chicken breasts
  • Kosher salt and freshly ground black pepper to taste
  • 15 ounces enchilada sauce 1 can
  • 14.5 ounces chopped tomatoes with green chilies drained (1 can)
  • 8 ounces sour cream
  • 1 cup Mexican blend shredded cheese

Optional Garnishes

  • Chopped fresh cilantro
  • Cojita cheese
  • Tortilla strips or corn chips

Instructions

  • Preheat oven to 375°F and spray an 8x11-inch baking dish with nonstick spray.
  • Pound the breasts to an even 1-inch thickness, then season both sides of the breasts with salt and black pepper.
    4 boneless, skinless chicken breasts, Kosher salt and freshly ground black pepper
    Four easy southwest chicken breasts on a cutting board.
  • Place the chicken in the prepared dish.
  • In a medium bowl, whisk together enchilada sauce, drained tomatoes, and sour cream.
    15 ounces enchilada sauce, 14.5 ounces chopped tomatoes with green chilies, 8 ounces sour cream
  • Pour the sauce/sour cream mixture over the chicken.
  • Bake at 375°F for 20-30 minutes, or until the internal temperature reaches 155°F.
  • Sprinkle breast with the Mexican blend cheese, then continue to cook just until the cheese is melted and beginning to bubble.
    1 cup Mexican blend shredded cheese
    A person is holding an easy casserole dish with cheese on it.
  • Remove chicken from the oven and allow to rest 3-4 minutes.
  • To serve, place a nest of tortilla chips on a plate and place the chicken on top. Drizzle with extra sauce and garnish with chopped cilantro & crumbled Cotija cheese. Serve with refried beans if desired.
    Chopped fresh cilantro, Cojita cheese, Tortilla strips

Video

Notes

  • Nutritional information does not include optional ingredients.
Storage: Store Southwestern chicken in an airtight container in the refrigerator for 3 days.

Nutrition

Calories: 514kcal | Carbohydrates: 16g | Protein: 41g | Fat: 31g | Saturated Fat: 17g | Cholesterol: 157mg | Sodium: 1582mg | Potassium: 754mg | Fiber: 3g | Sugar: 12g | Vitamin A: 1660IU | Vitamin C: 14.4mg | Calcium: 492mg | Iron: 2.6mg